MBTPS1

Across TCGA pan-cancer cohorts, MBTPS1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated MBTPS1 data layer compared with 23 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MBTPS1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MBTPS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

LUAD, CCRCC, and UCEC are the cancer types where MBTPS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.835	1.000	.008	9	view →
CCRCC	OS	Median	III,IV	0.104	0.977	.036	8	view →
UCEC	DFS	Median	All	0.923	0.786	.021	2	view →
PDAC	OS	Tertile	All	1.000	0.821	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

MBTPS1–LUAD (DFS)

Open the LUAD breakdown →