Across TCGA patient cohorts, MBP mutation is significantly associated with the RNA expression of many other genes, with 3,916 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MBP-associated genes across cancer lineages are MLLT10P2, RN7SL251P, and RNU7-56P. Each is linked with MBP in more than 2 cancer types. Because this analysis shows association rather than direction, both MBP-to-partner and partner-to-MBP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBP→partner) and Y-score (partner→MBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MLLT10P2 →	+0.327	+3.333	.009	.004	3	3
SKCM	RN7SL251P →	+0.154	+5.292	.004	.006	3	2
BRCA	RNU7-56P →	+1.070	+5.148	<.001	.008	3	2
BLCA	RNU6-81P →	+0.226	+4.814	<.001	.003	3	2
LUSC	AMELY →	+0.305	+4.154	<.001	.001	3	2
BLCA	OR2F1 →	+0.046	+4.618	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,916 associations by consensus.

Exploration

MBP survival (RNA) · tumor vs normal (RNA) · all MBP data types