MBP

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MBP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,407 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MBP-associated GO terms across cancer lineages are Negative regulation of actin filament polymerization, Viral gene expression, and Intracellular receptor signaling pathway. Each is linked with MBP in more than 9 cancer types. Because this analysis shows association rather than direction, both MBP-to-partner and partner-to-MBP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBP→partner) and Y-score (partner→MBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUENegative regulation of actin filament polymerization →+0.070+1.215.005<.001310
CNSViral gene expression →+0.079+1.865<.001.00139
SOFT_TISSUEIntracellular receptor signaling pathway →+0.041+1.033.002.00639
OVARYRho protein signal transduction →+0.091+1.834<.001<.00139
BREASTActin filament capping →+0.154+1.853<.001<.00139
CNSNegative regulation of supramolecular fiber organization →+0.066+1.780<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,407 associations by consensus.

Exploration