MBOAT2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MBOAT2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,003 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MBOAT2-associated genes across cancer lineages are SCEL, ASRGL1, and BCL2L1. Each is linked with MBOAT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both MBOAT2-to-partner and partner-to-MBOAT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MBOAT2 versus SCEL in PDAC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBOAT2→partner) and Y-score (partner→MBOAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACSCEL →+1.745+0.544<.001.00134
UCECASRGL1 →-0.996-0.935.003<.00134
LUADBCL2L1 →+0.496+0.566<.001<.00134
OVC19orf53 →+0.693+0.671<.001.00233
HNSCFNDC3A →-0.516-0.520.001<.00133
LUADPPARGC1A →-1.852-0.688<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,003 associations by consensus.

MBOAT2 vs SCEL — PDAC

Per-sample scatter of MBOAT2 vs SCEL in PDAC (Pearson r = 0.35).

Explore this scatter interactively →

Exploration