MBOAT2

Across TCGA cell cohorts, MBOAT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,943 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MBOAT2-associated GO terms across cancer lineages are Phosphatidylserine metabolic process, Regulation of post-translational protein modification, and Regulation of protein modification by small protein conjugation or removal. Each is linked with MBOAT2 in more than 12 cancer types. Because this analysis shows association rather than direction, both MBOAT2-to-partner and partner-to-MBOAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylserine metabolic process grouped by MBOAT2-low versus MBOAT2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBOAT2→partner) and Y-score (partner→MBOAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Phosphatidylserine metabolic process →	+0.113	+0.985	<.001	<.001	3	13
OVARY	Regulation of post-translational protein modification →	+0.075	+1.440	<.001	<.001	3	12
OVARY	Regulation of protein modification by small protein conjugation or removal →	+0.078	+1.379	<.001	<.001	3	11
BONE	Positive regulation of Wnt signaling pathway →	+0.053	+0.755	<.001	.004	3	10
KIDNEY	Negative regulation of mitotic cell cycle phase transition →	+0.038	+0.942	.006	.008	3	10
URINARY_TRACT	Negative regulation of organelle assembly →	+0.063	+1.270	.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,943 associations by consensus.

Phosphatidylserine metabolic process by MBOAT2 expression — CNS

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