MBNL3

Across TCGA patient cohorts, MBNL3 mutation is significantly associated with the RNA expression of many other genes, with 3,634 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MBNL3-associated genes across cancer lineages are RNA5SP419, OR3D1P, and LINC02559. Each is linked with MBNL3 in more than 2 cancer types. Because this analysis shows association rather than direction, both MBNL3-to-partner and partner-to-MBNL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by MBNL3-low versus MBNL3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBNL3→partner) and Y-score (partner→MBNL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.457	+2.077	<.001	<.001	3	3
GBM	OR3D1P →	+0.074	+5.352	<.001	.005	3	2
CESC	LINC02559 →	+1.780	+6.342	<.001	.001	3	2
CESC	NF1P10 →	+0.235	+6.569	<.001	.001	3	2
UCEC	LINC01072 →	+0.100	+2.073	<.001	<.001	3	2
UCEC	RNA5SP413 →	+0.783	+1.469	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,634 associations by consensus.

RNA5SP419 by MBNL3 expression — UCEC

Explore this box plot interactively →