MBNL3

Across TCGA cell cohorts, MBNL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,255 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MBNL3-associated GO terms across cancer lineages are Serotonin secretion, Serotonin production involved in inflammatory response, and Serotonin secretion involved in inflammatory response. Each is linked with MBNL3 in more than 11 cancer types. Because this analysis shows association rather than direction, both MBNL3-to-partner and partner-to-MBNL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Serotonin secretion grouped by MBNL3-low versus MBNL3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBNL3→partner) and Y-score (partner→MBNL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Serotonin secretion →	+1.849	+1.532	<.001	.007	3	12
LUNG_NSCLC_LUSC	Serotonin production involved in inflammatory response →	+1.849	+1.532	<.001	.007	3	12
LUNG_NSCLC_LUSC	Serotonin secretion involved in inflammatory response →	+1.849	+1.532	<.001	.007	3	12
LARGE_INTESTINE	Fertilization →	-0.083	-1.305	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Response to molecule of fungal origin →	+1.468	+1.574	<.001	<.001	3	10
PANCREAS	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →	-0.081	-1.012	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,255 associations by consensus.

Serotonin secretion by MBNL3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →