MBNL3

Across TCGA cell cohorts, MBNL3 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MBNL3-associated genes across cancer lineages are OR56B1, MSGN1, and LCN8. Each is linked with MBNL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MBNL3-to-partner and partner-to-MBNL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56B1 grouped by MBNL3-low versus MBNL3-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBNL3→partner) and Y-score (partner→MBNL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR56B1 →	+0.033	+4.228	<.001	.006	3	1
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1
LARGE_INTESTINE	LCN8 →	+0.166	+3.125	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR56B1 by MBNL3 expression — OVARY

Explore this box plot interactively →