MBNL2

Across TCGA patient cohorts, MBNL2 mutation is significantly associated with the RNA expression of many other genes, with 3,048 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MBNL2-associated genes across cancer lineages are MTND4LP2, MIR1302-2HG, and RPL10AP5. Each is linked with MBNL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MBNL2-to-partner and partner-to-MBNL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND4LP2 grouped by MBNL2-low versus MBNL2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBNL2→partner) and Y-score (partner→MBNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MTND4LP2 →	+0.189	+4.721	<.001	.004	3	2
READ	MIR1302-2HG →	+0.043	+4.421	<.001	.009	3	2
CESC	RPL10AP5 →	+0.069	+4.276	.001	.008	3	2
CESC	MIR3667 →	+0.714	+5.196	<.001	.001	3	2
CESC	MIR4510 →	+0.300	+5.342	<.001	.002	3	2
UCEC	RNA5SP138 →	+0.240	+2.453	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,048 associations by consensus.

MTND4LP2 by MBNL2 expression — COAD

Explore this box plot interactively →