MBNL2

Across TCGA cell cohorts, MBNL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,025 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MBNL2-associated GO terms across cancer lineages are Small GTPase-mediated signal transduction, Hormone-mediated signaling pathway, and Vesicle-mediated transport to the plasma membrane. Each is linked with MBNL2 in more than 13 cancer types. Because this analysis shows association rather than direction, both MBNL2-to-partner and partner-to-MBNL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Small GTPase-mediated signal transduction grouped by MBNL2-low versus MBNL2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBNL2→partner) and Y-score (partner→MBNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Small GTPase-mediated signal transduction →	+0.074	+1.600	<.001	<.001	3	14
BONE	Hormone-mediated signaling pathway →	+0.113	+1.795	<.001	<.001	3	14
BONE	Vesicle-mediated transport to the plasma membrane →	+0.069	+1.396	<.001	<.001	3	14
LIVER	Wound healing →	+0.121	+1.503	<.001	.002	3	13
SKIN	Regulation of protein monoubiquitination →	+0.190	+1.164	<.001	<.001	3	13
SKIN	Positive regulation of protein monoubiquitination →	+0.190	+1.164	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,025 associations by consensus.

Small GTPase-mediated signal transduction by MBNL2 expression — BONE

Explore this box plot interactively →