MBNL2

Across TCGA cell cohorts, MBNL2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MBNL2-associated genes across cancer lineages are PTF1A and C1QTNF7. Each is linked with MBNL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MBNL2-to-partner and partner-to-MBNL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTF1A grouped by MBNL2-low versus MBNL2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBNL2→partner) and Y-score (partner→MBNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PTF1A →	+0.135	+4.977	<.001	.007	3	1
LARGE_INTESTINE	C1QTNF7 →	+0.072	+4.108	.009	.008	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PTF1A by MBNL2 expression — SKIN

Explore this box plot interactively →