MBLAC2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MBLAC2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,159 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MBLAC2-associated genes across cancer lineages are CEP55, ARPC2, and GBP1. Each is linked with MBLAC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both MBLAC2-to-partner and partner-to-MBLAC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MBLAC2 versus CEP55 in OV, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBLAC2→partner) and Y-score (partner→MBLAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCEP55 →-0.863-0.336.001<.00135
LUADARPC2 →-0.387-0.281<.001<.00135
BRCAGBP1 →-1.160-0.466.004<.00134
CCRCCWDR17 →+0.768+0.222<.001<.00134
BRCAKCTD5 →-0.548-0.394.001<.00134
CCRCCEPB41L4A-AS1 →+0.668+0.234<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,159 associations by consensus.

MBLAC2 vs CEP55 — OV

Per-sample scatter of MBLAC2 vs CEP55 in OV (Pearson r = -0.40).

Explore this scatter interactively →

Exploration