MBIP

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MBIP RNA expression is significantly associated with the protein abundance of many other proteins, with 13,773 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MBIP-associated proteins across cancer lineages are CDC42BPB, DNAJC3, and MTA1_S449. Each is linked with MBIP in more than 3 cancer types. Because this analysis shows association rather than direction, both MBIP-to-partner and partner-to-MBIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MBIP versus CDC42BPB in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MBIP→partner) and Y-score (partner→MBIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCDC42BPB →+0.194+0.609<.001<.00134
COADDNAJC3 →-0.388-0.705<.001<.00134
PDACMTA1_S449 →+0.399+0.489.001.00234
GBMPPP2R5E →+0.304+0.557<.001<.00134
LSCCNEK9 →+0.159+0.538.002<.00134
GBMPYCARD →-0.502-0.416<.001.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,773 associations by consensus.

MBIP vs CDC42BPB — GBM

Per-sample scatter of MBIP vs CDC42BPB in GBM (Pearson r = 0.45).

Explore this scatter interactively →

Exploration