MBIP

Across TCGA patient cohorts, MBIP protein abundance is significantly associated with the RNA expression of many other genes, with 7,815 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MBIP-associated genes across cancer lineages are JADE3, C2orf68, and CLTRN. Each is linked with MBIP in more than 3 cancer types. Because this analysis shows association rather than direction, both MBIP-to-partner and partner-to-MBIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MBIP versus JADE3 in HNSC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBIP→partner) and Y-score (partner→MBIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	JADE3 →	+0.626	+0.256	.002	.002	3	4
HNSC	C2orf68 →	+0.546	+0.331	.001	.001	3	4
LUAD	CLTRN →	+0.717	+0.268	<.001	<.001	3	4
PDAC	PAIP2B →	+0.933	+0.338	.001	<.001	3	4
LSCC	HOOK1 →	+0.807	+0.216	<.001	<.001	3	4
LUAD	BRMS1L →	+0.683	+0.270	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,815 associations by consensus.

MBIP vs JADE3 — HNSC

Explore this scatter interactively →