MBIP

Across TCGA cell cohorts, MBIP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,408 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MBIP-associated GO terms across cancer lineages are Monoubiquitinated protein deubiquitination, Vesicle tethering, and Protein localization to condensed chromosome. Each is linked with MBIP in more than 10 cancer types. Because this analysis shows association rather than direction, both MBIP-to-partner and partner-to-MBIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monoubiquitinated protein deubiquitination grouped by MBIP-low versus MBIP-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBIP→partner) and Y-score (partner→MBIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Monoubiquitinated protein deubiquitination →	+0.141	+1.088	<.001	<.001	3	11
KIDNEY	Vesicle tethering →	+0.074	+0.762	<.001	<.001	3	11
OVARY	Protein localization to condensed chromosome →	+0.118	+0.790	.002	.006	2	11
LUNG_SCLC	Vesicle coating →	+0.104	+1.083	<.001	.002	3	10
SKIN	Regulation of protein deacetylation →	+0.123	+0.852	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Actin filament fragmentation →	+0.119	+1.552	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,408 associations by consensus.

Monoubiquitinated protein deubiquitination by MBIP expression — BLOOD_Myeloma

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