MBD6

Across TCGA patient cohorts, MBD6 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,903 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MBD6-associated proteins across cancer lineages are C1orf116_S519, PPIG, and RBM12B_S280. Each is linked with MBD6 in more than 2 cancer types. Because this analysis shows association rather than direction, both MBD6-to-partner and partner-to-MBD6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MBD6 versus C1orf116_S519 in BRCA, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD6→partner) and Y-score (partner→MBD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	C1orf116_S519 →	-1.607	-1.007	<.001	<.001	3	3
LSCC	PPIG →	+0.264	+0.555	<.001	<.001	3	3
HNSC	RBM12B_S280 →	+0.734	+0.751	<.001	.002	3	3
LSCC	IARS2 →	+0.390	+0.607	<.001	<.001	3	3
BRCA	RIF1_S1454 →	-0.991	-1.086	<.001	<.001	3	3
BRCA	SEC61B_S17 →	-0.638	-0.843	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,903 associations by consensus.

MBD6 vs C1orf116_S519 — BRCA

Explore this scatter interactively →