MBD6

Across TCGA cell cohorts, MBD6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,037 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MBD6-associated GO terms across cancer lineages are Oocyte growth, Positive regulation of TORC2 signaling, and Negative regulation of myoblast fusion. Each is linked with MBD6 in more than 16 cancer types. Because this analysis shows association rather than direction, both MBD6-to-partner and partner-to-MBD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oocyte growth grouped by MBD6-low versus MBD6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD6→partner) and Y-score (partner→MBD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Oocyte growth →	+0.211	+1.037	<.001	<.001	3	17
SKIN	Positive regulation of TORC2 signaling →	+0.100	+0.576	<.001	.002	3	16
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.114	+1.078	<.001	<.001	3	14
BONE	Pre-mRNA catabolic process →	+0.345	+1.517	<.001	<.001	3	14
STOMACH	Protein destabilization →	+0.105	+0.887	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.144	+0.660	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,037 associations by consensus.

Oocyte growth by MBD6 expression — BONE

Explore this box plot interactively →