Across TCGA patient cohorts, MBD5 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,774 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MBD5-associated proteins across cancer lineages are RPL26, RO60, and RPL3. Each is linked with MBD5 in more than 5 cancer types. Because this analysis shows association rather than direction, both MBD5-to-partner and partner-to-MBD5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD5→partner) and Y-score (partner→MBD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL26 →	-0.815	-0.487	<.001	<.001	3	6
GBM	RO60 →	+0.239	+0.411	<.001	<.001	3	5
GBM	RPL3 →	-0.328	-0.385	<.001	<.001	3	5
GBM	ERO1A →	-0.681	-0.411	<.001	<.001	3	5
GBM	AGO1 →	+0.264	+0.470	<.001	<.001	3	5
LSCC	ABI2 →	+0.462	+0.464	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,774 associations by consensus.

Exploration

MBD5 survival (RNA) · tumor vs normal (RNA) · all MBD5 data types