Across TCGA cell cohorts, MBD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,165 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MBD5-associated GO terms across cancer lineages are Autophagy, Retrograde transport, endosome to Golgi, and Positive regulation of growth hormone receptor signaling pathway. Each is linked with MBD5 in more than 15 cancer types. Because this analysis shows association rather than direction, both MBD5-to-partner and partner-to-MBD5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD5→partner) and Y-score (partner→MBD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Autophagy →	+0.071	+0.817	<.001	.002	3	16
KIDNEY	Retrograde transport, endosome to Golgi →	+0.076	+0.773	.005	.009	3	16
SOFT_TISSUE	Positive regulation of growth hormone receptor signaling pathway →	+1.038	+0.852	<.001	<.001	3	16
OESOPHAGUS	Cytosolic transport →	+0.088	+0.836	.001	.007	3	16
KIDNEY	Process utilizing autophagic mechanism →	+0.071	+0.817	<.001	.002	3	16
OESOPHAGUS	Establishment of protein localization to vacuole →	+0.099	+0.897	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,165 associations by consensus.

Exploration

MBD5 survival (RNA) · tumor vs normal (RNA) · all MBD5 data types