MBD4

Across TCGA cell cohorts, MBD4 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MBD4-associated genes across cancer lineages are SPRR2F. Each is linked with MBD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both MBD4-to-partner and partner-to-MBD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPRR2F grouped by MBD4-low versus MBD4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD4→partner) and Y-score (partner→MBD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SPRR2F →	+0.477	+3.707	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SPRR2F by MBD4 expression — LARGE_INTESTINE

Explore this box plot interactively →