MBD3L5

Across TCGA patient cohorts, MBD3L5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,817 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MBD3L5-associated GO terms across cancer lineages are Respiratory electron transport chain, Positive regulation of signal transduction by p53 class mediator, and Proton transmembrane transport. Each is linked with MBD3L5 in more than 4 cancer types. Because this analysis shows association rather than direction, both MBD3L5-to-partner and partner-to-MBD3L5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Respiratory electron transport chain grouped by MBD3L5-low versus MBD3L5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD3L5→partner) and Y-score (partner→MBD3L5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Respiratory electron transport chain →	+0.163	+0.012	<.001	.001	3	4
STAD	Positive regulation of signal transduction by p53 class mediator →	+0.131	+0.013	<.001	<.001	3	4
STAD	Proton transmembrane transport →	+0.119	+0.016	<.001	.001	3	4
STAD	ATP synthesis coupled electron transport →	+0.170	+0.013	<.001	<.001	3	4
STAD	Aerobic respiration →	+0.163	+0.022	<.001	<.001	3	4
STAD	Nucleoside triphosphate biosynthetic process →	+0.167	+0.025	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,817 associations by consensus.

Respiratory electron transport chain by MBD3L5 expression — STAD

Explore this box plot interactively →