MBD3

Across TCGA patient cohorts, MBD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,006 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MBD3-associated proteins across cancer lineages are RRM1, ATAD2, and CHAF1A_S65. Each is linked with MBD3 in more than 4 cancer types. Because this analysis shows association rather than direction, both MBD3-to-partner and partner-to-MBD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MBD3 versus RRM1 in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD3→partner) and Y-score (partner→MBD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RRM1 →	+0.656	+0.508	<.001	<.001	3	5
LUAD	ATAD2 →	+0.544	+0.436	<.001	<.001	3	5
LSCC	CHAF1A_S65 →	+0.848	+0.679	<.001	<.001	3	5
OV	SGTA →	+0.338	+0.625	<.001	.001	3	5
GBM	REPIN1 →	+0.346	+0.378	.002	<.001	3	4
LSCC	RFC1_S368 →	+0.769	+0.509	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,006 associations by consensus.

MBD3 vs RRM1 — LSCC

Explore this scatter interactively →