MBD1

Across TCGA patient cohorts, MBD1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,045 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MBD1-associated genes across cancer lineages are RELCH, TXNL1, and DYM. Each is linked with MBD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MBD1-to-partner and partner-to-MBD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MBD1 versus RELCH in HNSC, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD1→partner) and Y-score (partner→MBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RELCH →	+0.400	+0.181	.001	.007	3	6
OV	TXNL1 →	+0.521	+0.370	<.001	<.001	3	6
HNSC	DYM →	+0.483	+0.198	<.001	.001	3	5
BRCA	CXXC1 →	+0.781	+0.432	<.001	<.001	3	5
HNSC	ZNF407 →	+0.427	+0.257	.002	<.001	3	5
OV	ELAC1 →	+0.578	+0.431	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,045 associations by consensus.

MBD1 vs RELCH — HNSC

Explore this scatter interactively →