Across TCGA patient cohorts, MB RNA expression is significantly associated with the protein abundance of many other proteins, with 14,536 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MB-associated proteins across cancer lineages are AP1M2, GSTZ1, and UGP2. Each is linked with MB in more than 5 cancer types. Because this analysis shows association rather than direction, both MB-to-partner and partner-to-MB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MB→partner) and Y-score (partner→MB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AP1M2 →	+0.516	+1.137	<.001	.005	3	5
OV	GSTZ1 →	+0.501	+1.067	.002	.006	2	6
HNSC	UGP2 →	+0.317	+2.571	<.001	<.001	3	4
HNSC	UTP4 →	-0.318	-3.140	<.001	<.001	3	4
BRCA	MYO5C →	+0.464	+0.978	<.001	<.001	3	4
BRCA	SGSM3 →	+0.517	+1.199	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,536 associations by consensus.

Exploration

MB survival (RNA) · tumor vs normal (RNA) · all MB data types