Across TCGA cell cohorts, MB protein abundance is significantly associated with the RNA expression of many other genes, with 377 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MB-associated genes across cancer lineages are ARRDC3, EPAS1, and ZC2HC1C. Each is linked with MB in more than 2 cancer types. Because this analysis shows association rather than direction, both MB-to-partner and partner-to-MB results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MB→partner) and Y-score (partner→MB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	ARRDC3 →	-1.262	-2.285	.004	<.001	3	3
OESOPHAGUS	EPAS1 →	-3.438	-4.324	.008	.002	3	2
OESOPHAGUS	ZC2HC1C →	-0.942	-4.324	.003	.002	3	2
OESOPHAGUS	SMPDL3B →	-2.520	-4.324	<.001	.002	3	2
OESOPHAGUS	HIGD2A →	+1.125	+4.324	<.001	.002	3	2
BLOOD_Leukemia	MYZAP →	-0.073	-2.565	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 377 associations by consensus.

Exploration

MB survival (RNA) · tumor vs normal (RNA) · all MB data types