MAU2

Across TCGA cell cohorts, MAU2 mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAU2-associated genes across cancer lineages are SCN2A, C16orf92, and SPATA3. Each is linked with MAU2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAU2-to-partner and partner-to-MAU2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCN2A grouped by MAU2-low versus MAU2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAU2→partner) and Y-score (partner→MAU2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SCN2A →	+0.665	+3.321	.002	.009	3	2
BLOOD_Leukemia	C16orf92 →	+0.121	+3.359	.001	.002	3	2
BLOOD_Myeloma	SPATA3 →	+0.080	+4.807	<.001	.006	3	1
BLOOD_Myeloma	CLEC19A →	+0.133	+4.807	<.001	.006	3	1
URINARY_TRACT	CLEC20A →	+0.373	+4.050	.003	.002	3	1
SKIN	OR7A10 →	+0.017	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

SCN2A by MAU2 expression — BLOOD_Leukemia

Explore this box plot interactively →