MATR3

Across TCGA cell cohorts, MATR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,249 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MATR3-associated GO terms across cancer lineages are Mitotic spindle assembly, Centrosome duplication, and DNA-templated DNA replication. Each is linked with MATR3 in more than 18 cancer types. Because this analysis shows association rather than direction, both MATR3-to-partner and partner-to-MATR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle assembly grouped by MATR3-low versus MATR3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MATR3→partner) and Y-score (partner→MATR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Mitotic spindle assembly →	+0.105	+0.879	.001	.006	3	19
STOMACH	Centrosome duplication →	+0.097	+0.712	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.107	+0.877	<.001	<.001	3	19
PANCREAS	Protein import into nucleus →	+0.068	+0.706	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.076	+1.075	.002	<.001	3	18
STOMACH	Mitotic sister chromatid segregation →	+0.110	+0.643	.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,249 associations by consensus.

Mitotic spindle assembly by MATR3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →