MATR3

Across TCGA cell cohorts, MATR3 mutation is significantly associated with the RNA expression of many other genes, with 364 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MATR3-associated genes across cancer lineages are OPN1MW2, OR1E1, and CYP39A1. Each is linked with MATR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MATR3-to-partner and partner-to-MATR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPN1MW2 grouped by MATR3-low versus MATR3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MATR3→partner) and Y-score (partner→MATR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OPN1MW2 →	+0.063	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR1E1 →	+0.115	+4.078	<.001	.009	3	1
BLOOD_Leukemia	CYP39A1 →	+0.131	+3.091	<.001	.006	3	1
BLOOD_Leukemia	AQP12A →	+0.063	+3.269	<.001	.007	3	1
BLOOD_Leukemia	BRINP2 →	+0.182	+3.469	<.001	.004	3	1
BLOOD_Leukemia	SPEM3 →	+0.008	+3.239	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 364 associations by consensus.

OPN1MW2 by MATR3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →