MATN3

Across TCGA patient cohorts, MATN3 mutation is significantly associated with the RNA expression of many other genes, with 1,659 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MATN3-associated genes across cancer lineages are RN7SL680P, GPN2, and RNU6-1318P. Each is linked with MATN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MATN3-to-partner and partner-to-MATN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL680P grouped by MATN3-low versus MATN3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MATN3→partner) and Y-score (partner→MATN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL680P →	+0.112	+4.219	<.001	.006	3	2
UCEC	GPN2 →	+0.399	+3.332	.001	.005	3	2
UCEC	RNU6-1318P →	+0.273	+2.658	<.001	.005	3	2
SKCM	RN7SKP286 →	+0.051	+4.810	<.001	.002	3	2
UCEC	RNA5SP408 →	+0.296	+2.486	.001	.008	3	2
SKCM	RNY4P7 →	+0.344	+3.132	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,659 associations by consensus.

RN7SL680P by MATN3 expression — SKCM

Explore this box plot interactively →