MATN1

Across TCGA patient cohorts, MATN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,137 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MATN1-associated GO terms across cancer lineages are Maintenance of cell number, RNA secondary structure unwinding, and TOR signaling. Each is linked with MATN1 in more than 27 cancer types. Because this analysis shows association rather than direction, both MATN1-to-partner and partner-to-MATN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of cell number grouped by MATN1-low versus MATN1-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MATN1→partner) and Y-score (partner→MATN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Maintenance of cell number →	+0.076	+0.706	<.001	.001	3	27
ESCA	RNA secondary structure unwinding →	+0.067	+0.098	.001	<.001	3	26
SCLC	TOR signaling →	+0.070	+0.358	<.001	.003	2	27
SCLC	Epigenetic regulation of gene expression →	+0.081	+0.570	<.001	<.001	3	26
SCLC	Dendrite morphogenesis →	+0.097	+0.676	<.001	<.001	3	26
ESCA	Smoothened signaling pathway →	+0.046	+0.074	.002	.009	1	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,137 associations by consensus.

Maintenance of cell number by MATN1 expression — SCLC

Explore this box plot interactively →