MAST4

Across TCGA patient cohorts, MAST4 protein abundance is significantly associated with the RNA expression of many other genes, with 17,068 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MAST4-associated genes across cancer lineages are AURKA, MAST4-AS1, and ORC6. Each is linked with MAST4 in more than 6 cancer types. Because this analysis shows association rather than direction, both MAST4-to-partner and partner-to-MAST4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAST4 versus AURKA in UCEC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAST4→partner) and Y-score (partner→MAST4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AURKA →	-1.433	-0.473	<.001	<.001	3	7
CCRCC	MAST4-AS1 →	+1.024	+0.359	<.001	<.001	3	7
BRCA	ORC6 →	-0.774	-0.430	<.001	<.001	3	7
LUAD	MYBL2 →	-1.536	-0.305	<.001	<.001	3	6
LUAD	NCAPG →	-0.982	-0.276	<.001	<.001	3	6
UCEC	TTK →	-1.307	-0.414	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,068 associations by consensus.

MAST4 vs AURKA — UCEC

Explore this scatter interactively →