MAST2

Across TCGA patient cohorts, MAST2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,804 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MAST2-associated genes across cancer lineages are CYP27C1, RPS26P20, and PDGFRL. Each is linked with MAST2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAST2-to-partner and partner-to-MAST2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAST2 versus CYP27C1 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAST2→partner) and Y-score (partner→MAST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CYP27C1 →	+0.692	+0.320	.003	.004	3	3
LSCC	RPS26P20 →	-0.511	-0.295	<.001	.002	3	3
OV	PDGFRL →	+0.835	+0.328	.006	.006	3	2
OV	GASK1B →	+0.948	+0.431	.002	.004	3	2
OV	CAPZA1P3 →	-0.504	-0.428	.003	.001	3	2
LSCC	TPM1-AS →	+0.327	+0.330	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,804 associations by consensus.

MAST2 vs CYP27C1 — UCEC

Explore this scatter interactively →