MAST2

Across TCGA cell cohorts, MAST2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,512 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAST2-associated GO terms across cancer lineages are Cytosolic transport, Negative regulation of DNA-templated transcription initiation, and Regulation of centriole-centriole cohesion. Each is linked with MAST2 in more than 16 cancer types. Because this analysis shows association rather than direction, both MAST2-to-partner and partner-to-MAST2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by MAST2-low versus MAST2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAST2→partner) and Y-score (partner→MAST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Cytosolic transport →	+0.069	+0.982	.004	.004	3	17
SOFT_TISSUE	Negative regulation of DNA-templated transcription initiation →	+0.122	+1.010	<.001	<.001	3	15
SKIN	Regulation of centriole-centriole cohesion →	+0.138	+0.984	<.001	<.001	3	15
SOFT_TISSUE	Negative regulation of transcription initiation by RNA polymerase II →	+0.122	+1.010	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.060	+1.121	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of autophagosome maturation →	+0.120	+1.194	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,512 associations by consensus.

Cytosolic transport by MAST2 expression — KIDNEY

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