MASP2

Across TCGA patient cohorts, MASP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,650 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MASP2-associated proteins across cancer lineages are ZNF704_S77, LRRC47_S431, and S100A9. Each is linked with MASP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both MASP2-to-partner and partner-to-MASP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MASP2 versus ZNF704_S77 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MASP2→partner) and Y-score (partner→MASP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF704_S77 →	+0.792	+0.757	<.001	<.001	3	6
LSCC	LRRC47_S431 →	+0.607	+0.402	.002	.001	3	6
GBM	S100A9 →	-1.089	-0.606	.001	<.001	3	6
HNSC	PGAM1_S31 →	-0.634	-0.626	<.001	<.001	3	5
BRCA	RERE_S656 →	+0.510	+0.534	<.001	<.001	3	5
PDAC	UBL4A_S90 →	+0.690	+0.337	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,650 associations by consensus.

MASP2 vs ZNF704_S77 — BRCA

Explore this scatter interactively →