MARVELD1

Across TCGA patient cohorts, MARVELD1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MARVELD1-associated genes across cancer lineages are NMTRQ-TTG12-1, DLGAP2-AS1, and IGHVIII-2-1. Each is linked with MARVELD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MARVELD1-to-partner and partner-to-MARVELD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NMTRQ-TTG12-1 grouped by MARVELD1-low versus MARVELD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARVELD1→partner) and Y-score (partner→MARVELD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NMTRQ-TTG12-1 →	+0.746	+5.358	<.001	.006	3	1
UCEC	DLGAP2-AS1 →	+0.098	+5.694	<.001	.003	3	1
UCEC	IGHVIII-2-1 →	+0.269	+6.027	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

NMTRQ-TTG12-1 by MARVELD1 expression — UCEC

Explore this box plot interactively →