MARS2

Across TCGA patient cohorts, MARS2 mutation is significantly associated with the RNA expression of many other genes, with 3,315 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MARS2-associated genes across cancer lineages are MIR4672, RNA5SP79, and CALM1P2. Each is linked with MARS2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MARS2-to-partner and partner-to-MARS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4672 grouped by MARS2-low versus MARS2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARS2→partner) and Y-score (partner→MARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR4672 →	+0.690	+2.584	<.001	.005	3	3
CESC	RNA5SP79 →	+0.244	+4.010	.001	.002	3	2
CESC	CALM1P2 →	+0.205	+4.455	<.001	<.001	3	2
SARC	RNU5A-3P →	+0.439	+5.224	<.001	.006	3	2
COAD	PHF5A →	+0.526	+3.223	.002	.008	3	2
COAD	ZIC5 →	+1.300	+3.267	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,315 associations by consensus.

MIR4672 by MARS2 expression — COAD

Explore this box plot interactively →