MARS2

Across TCGA cell cohorts, MARS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,299 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MARS2-associated GO terms across cancer lineages are Mitochondrial large ribosomal subunit assembly, Mitochondrial RNA metabolic process, and Ribosomal large subunit assembly. Each is linked with MARS2 in more than 18 cancer types. Because this analysis shows association rather than direction, both MARS2-to-partner and partner-to-MARS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial large ribosomal subunit assembly grouped by MARS2-low versus MARS2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MARS2→partner) and Y-score (partner→MARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Mitochondrial large ribosomal subunit assembly →	+0.129	+0.937	.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Mitochondrial RNA metabolic process →	+0.098	+1.030	<.001	<.001	3	18
BONE	Ribosomal large subunit assembly →	+0.130	+0.995	.002	.001	3	18
BLOOD_Lymphoma	Maturation of SSU-rRNA →	+0.114	+0.912	<.001	<.001	3	17
LIVER	rRNA modification →	+0.118	+0.999	<.001	<.001	3	17
BONE	rRNA metabolic process →	+0.094	+0.840	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,299 associations by consensus.

Mitochondrial large ribosomal subunit assembly by MARS2 expression — LIVER

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