MARK3P3

Across TCGA pan-cancer cohorts, MARK3P3 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated MARK3P3 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MARK3P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MARK3P3 expression acts as an unfavorable survival marker, although some lineages such as DLBC and CHOL show a favorable association.

COAD, KIRP, and STAD are the cancer types where MARK3P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.309	0.557	<.001	117	view →
KIRP	DFS	Tertile	All	0.750	0.894	<.001	58	view →
STAD	DFS	Tertile	All	0.259	0.484	.003	42	view →
LIHC	OS	Tertile	III,IV	0.334	0.636	.013	33	view →
THYM	OS	Tertile	All	0.894	0.981	.023	27	view →
UCEC	DFS	Tertile	II,III,IV	0.596	0.758	.022	24	view →
DLBC	DFS	Tertile	All	1.000	0.455	.014	22	view →
BLCA	OS	Quartile	III,IV	0.227	0.398	.011	21	view →
PAAD	DFS	Tertile	All	0.334	0.534	.017	21	view →
READ	DFS	Tertile	III,IV	0.503	0.798	.009	18	view →
UVM	OS	Tertile	All	0.367	0.730	.015	12	view →
LUSC	DFS	Median	III,IV	0.231	0.459	.028	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

MARK3P3–COAD (DFS)

Open the COAD breakdown →