MARK3

Across TCGA patient cohorts, MARK3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,108 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MARK3-associated genes across cancer lineages are EIF5, PSMC1, and CINP. Each is linked with MARK3 in more than 6 cancer types. Because this analysis shows association rather than direction, both MARK3-to-partner and partner-to-MARK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MARK3 versus EIF5 in HNSC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARK3→partner) and Y-score (partner→MARK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EIF5 →	+0.677	+0.267	<.001	<.001	3	7
HNSC	PSMC1 →	+0.922	+0.281	.002	.001	3	7
LSCC	CINP →	+0.525	+0.306	<.001	<.001	3	7
HNSC	ATP5MPL →	+0.682	+0.255	<.001	<.001	3	7
HNSC	TRAPPC6B →	+0.645	+0.256	<.001	.001	3	7
HNSC	CALM1 →	+0.666	+0.189	.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,108 associations by consensus.

MARK3 vs EIF5 — HNSC

Explore this scatter interactively →