MARK3

Across TCGA cell cohorts, MARK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,643 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MARK3-associated GO terms across cancer lineages are Regulation of ubiquitin-dependent protein catabolic process, Microtubule nucleation, and Establishment of mitotic spindle localization. Each is linked with MARK3 in more than 15 cancer types. Because this analysis shows association rather than direction, both MARK3-to-partner and partner-to-MARK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of ubiquitin-dependent protein catabolic process grouped by MARK3-low versus MARK3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MARK3→partner) and Y-score (partner→MARK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of ubiquitin-dependent protein catabolic process →	+0.077	+0.806	.006	.003	3	16
OVARY	Microtubule nucleation →	+0.103	+0.763	<.001	<.001	3	15
LIVER	Establishment of mitotic spindle localization →	+0.108	+0.871	.004	.001	3	15
URINARY_TRACT	miRNA processing →	+0.089	+0.827	.007	.003	3	15
BLOOD_Leukemia	Microtubule polymerization →	+0.116	+0.560	<.001	<.001	3	15
OESOPHAGUS	Regulation of mRNA splicing, via spliceosome →	+0.082	+0.629	.004	.003	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,643 associations by consensus.

Regulation of ubiquitin-dependent protein catabolic process by MARK3 expression — OESOPHAGUS

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