MARK2P8

Across TCGA pan-cancer cohorts, MARK2P8 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated MARK2P8 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher MARK2P8 RNA is associated with better overall survival. In most high-consensus cancer types, elevated MARK2P8 expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

UCS, ACC, and BRCA are the cancer types where MARK2P8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	II,III,IV	0.574	0.233	.002	82	view →
ACC	DFS	Tertile	III,IV	0.046	0.670	.001	20	view →
BRCA	DFS	Tertile	IV	0.602	0.202	.013	18	view →
LGG	DFS	Quartile	All	0.763	0.862	.008	16	view →
COAD	OS	Median	IV	0.872	0.392	.002	14	view →
UCEC	OS	Quartile	II,III,IV	0.795	0.881	.024	12	view →
KIRC	DFS	Median	II,III,IV	0.334	0.618	.008	10	view →
THCA	OS	Median	IV	1.000	0.607	.006	5	view →
HNSC	OS	Quartile	II,III,IV	0.831	0.721	.024	5	view →
SKCM	OS	Median	III,IV	0.748	0.914	.013	5	view →
OV	OS	Median	III,IV	0.804	0.864	.011	4	view →
LAML	DFS	Tertile	All	0.541	0.288	.042	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

MARK2P8–UCS (OS)

Open the UCS breakdown →