MARK2P11

Across TCGA patient cohorts, MARK2P11 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,176 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MARK2P11-associated GO terms across cancer lineages are Positive regulation of proteasomal ubiquitin-dependent protein catabolic process, Positive regulation of establishment of protein localization to telomere, and Protein folding. Each is linked with MARK2P11 in more than 9 cancer types. Because this analysis shows association rather than direction, both MARK2P11-to-partner and partner-to-MARK2P11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of proteasomal ubiquitin-dependent protein catabolic process grouped by MARK2P11-low versus MARK2P11-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MARK2P11→partner) and Y-score (partner→MARK2P11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.092	+0.240	<.001	<.001	3	10
STAD	Positive regulation of establishment of protein localization to telomere →	+0.094	+0.202	<.001	.001	3	10
STAD	Protein folding →	+0.091	+0.213	<.001	<.001	3	10
ESCA	Water-soluble vitamin metabolic process →	+0.039	+0.139	<.001	<.001	3	9
ESCA	Organelle membrane fusion →	+0.069	+0.181	<.001	<.001	3	9
STAD	Aerobic respiration →	+0.102	+0.231	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,176 associations by consensus.

Positive regulation of proteasomal ubiquitin-dependent protein catabolic process by MARK2P11 expression — STAD

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