MARK1

Across TCGA patient cohorts, MARK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,812 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MARK1-associated proteins across cancer lineages are MARK1_S649, MARK1_S468, and MARK1_T504. Each is linked with MARK1 in more than 8 cancer types. Because this analysis shows association rather than direction, both MARK1-to-partner and partner-to-MARK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MARK1 versus MARK1_S649 in OV, with a Pearson correlation of 0.88.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MARK1→partner) and Y-score (partner→MARK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MARK1_S649 →	+1.660	+1.175	.002	.009	3	9
BRCA	MARK1_S468 →	+1.053	+0.899	<.001	<.001	3	8
OV	MARK1_T504 →	+1.363	+0.802	.001	.001	3	8
HNSC	PSME2 →	-0.401	-0.615	<.001	<.001	3	7
HNSC	TRIM21 →	-0.450	-0.533	<.001	<.001	3	6
BRCA	MARK1_S382 →	+2.102	+2.109	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,812 associations by consensus.

MARK1 vs MARK1_S649 — OV

Explore this scatter interactively →