MARF1

Across TCGA cell cohorts, MARF1 mutation is significantly associated with the RNA expression of many other genes, with 672 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MARF1-associated genes across cancer lineages are IL5, CLEC4F, and HTR3C. Each is linked with MARF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MARF1-to-partner and partner-to-MARF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL5 grouped by MARF1-low versus MARF1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARF1→partner) and Y-score (partner→MARF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IL5 →	+0.207	+3.853	<.001	.002	3	2
BLOOD_Leukemia	CLEC4F →	+0.058	+3.643	.002	.006	3	2
STOMACH	HTR3C →	+0.042	+2.954	.001	.005	3	2
LARGE_INTESTINE	PSMG2 →	+0.429	+3.169	.004	.006	3	2
LARGE_INTESTINE	ENTPD1 →	+0.532	+3.237	<.001	.003	3	2
LARGE_INTESTINE	TDRD5 →	+0.503	+2.043	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 672 associations by consensus.

IL5 by MARF1 expression — BLOOD_Leukemia

Explore this box plot interactively →