MARCOL

Across TCGA pan-cancer cohorts, MARCOL RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated MARCOL data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher MARCOL RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MARCOL expression acts as an unfavorable survival marker, although some lineages such as PAAD and UCEC show a favorable association.

PAAD, UCS, and UCEC are the cancer types where MARCOL RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	DFS	Tertile	All	0.714	0.401	.002	36	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
UCEC	OS	Tertile	II,III,IV	1.000	0.514	.034	36	view →
STAD	DFS	Tertile	II,III,IV	0.320	0.558	.022	27	view →
ACC	DFS	Quartile	All	0.385	0.826	.002	25	view →
READ	DFS	Tertile	III,IV	0.430	0.781	.006	21	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
TGCT	OS	Tertile	All	0.845	0.968	.017	18	view →
PCPG	OS	Tertile	All	0.881	0.985	.004	18	view →
KICH	DFS	Median	II,III,IV	1.000	0.487	.012	14	view →
BLCA	DFS	Tertile	IV	1.000	0.308	.036	9	view →
SKCM	DFS	Tertile	IV	0.040	0.432	.038	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

MARCOL–PAAD (DFS)

Open the PAAD breakdown →