MARCHF9

Across TCGA patient cohorts, MARCHF9 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MARCHF9-associated genes across cancer lineages are B-cells, pDC, and Basophils. Each is linked with MARCHF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both MARCHF9-to-partner and partner-to-MARCHF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B-cells grouped by MARCHF9-low versus MARCHF9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF9→partner) and Y-score (partner→MARCHF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	B-cells →	+0.054	+1.895	<.001	.048	3	1
UCEC	pDC →	+0.061	+2.815	.030	.036	2	2
UCEC	Basophils →	+0.333	+3.000	<.001	.037	2	1
UCEC	CMP →	-0.038	-2.989	.032	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

B-cells by MARCHF9 expression — UCEC

Explore this box plot interactively →