MARCHF9

Across TCGA cell cohorts, MARCHF9 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MARCHF9-associated genes across cancer lineages are SMR3B, OR4F4, and TSPY8. Each is linked with MARCHF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both MARCHF9-to-partner and partner-to-MARCHF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMR3B grouped by MARCHF9-low versus MARCHF9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF9→partner) and Y-score (partner→MARCHF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SMR3B →	+0.968	+4.467	<.001	.004	3	1
LARGE_INTESTINE	OR4F4 →	+0.020	+4.273	<.001	.006	3	1
LARGE_INTESTINE	TSPY8 →	+0.102	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

SMR3B by MARCHF9 expression — LARGE_INTESTINE

Explore this box plot interactively →