MARCHF8

Across TCGA patient cohorts, MARCHF8 protein abundance is significantly associated with the RNA expression of many other genes, with 623 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MARCHF8-associated genes across cancer lineages are UPK3A, RPS6KA5, and GATA1. Each is linked with MARCHF8 in more than 1 cancer types. Because this analysis shows association rather than direction, both MARCHF8-to-partner and partner-to-MARCHF8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MARCHF8 versus UPK3A in LUAD, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF8→partner) and Y-score (partner→MARCHF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	UPK3A →	+1.775	+0.861	<.001	.001	3	1
LUAD	RPS6KA5 →	+0.968	+1.010	.002	.001	3	1
LUAD	GATA1 →	+0.875	+0.890	.001	.001	3	1
LUAD	KLF8 →	+1.324	+0.860	.004	.003	3	1
LUAD	ZDHHC15 →	+1.508	+1.045	.001	.004	3	1
LUAD	CCL22 →	+1.206	+0.939	.007	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 623 associations by consensus.

MARCHF8 vs UPK3A — LUAD

Explore this scatter interactively →