MARCHF7

Across TCGA cell cohorts, MARCHF7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,438 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MARCHF7-associated GO terms across cancer lineages are Regulation of endoplasmic reticulum tubular network organization, Regulation of microtubule-based process, and Positive regulation of cell cycle. Each is linked with MARCHF7 in more than 14 cancer types. Because this analysis shows association rather than direction, both MARCHF7-to-partner and partner-to-MARCHF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of endoplasmic reticulum tubular network organization grouped by MARCHF7-low versus MARCHF7-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF7→partner) and Y-score (partner→MARCHF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of endoplasmic reticulum tubular network organization →	+0.101	+1.143	<.001	<.001	3	15
LUNG_SCLC	Regulation of microtubule-based process →	+0.053	+0.625	.002	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle →	+0.066	+0.717	<.001	.007	3	14
SOFT_TISSUE	Monoubiquitinated protein deubiquitination →	+0.140	+0.859	<.001	<.001	3	14
STOMACH	7-methylguanosine mRNA capping →	+0.107	+0.815	<.001	.001	3	14
STOMACH	7-methylguanosine RNA capping →	+0.107	+0.815	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,438 associations by consensus.

Regulation of endoplasmic reticulum tubular network organization by MARCHF7 expression — OESOPHAGUS

Explore this box plot interactively →