MARCHF6

Across TCGA patient cohorts, MARCHF6 protein abundance is significantly associated with the RNA expression of many other genes, with 3,227 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MARCHF6-associated genes across cancer lineages are DAP, ATPSCKMT, and ICE1. Each is linked with MARCHF6 in more than 2 cancer types. Because this analysis shows association rather than direction, both MARCHF6-to-partner and partner-to-MARCHF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MARCHF6 versus DAP in LSCC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF6→partner) and Y-score (partner→MARCHF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DAP →	+0.859	+0.369	<.001	<.001	3	3
LSCC	ATPSCKMT →	+0.863	+0.364	<.001	<.001	3	3
LSCC	ICE1 →	+0.601	+0.309	<.001	.003	3	3
LSCC	CCDC127 →	+0.616	+0.345	<.001	<.001	3	3
LSCC	TOMM20 →	+0.450	+0.320	.003	<.001	3	3
LSCC	CLPTM1L →	+0.618	+0.366	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,227 associations by consensus.

MARCHF6 vs DAP — LSCC

Explore this scatter interactively →